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Adjustments to diabetes medications might be needed to maintain glycemic control
A recent pilot study revealed that both PWS and obese patients (n=8 and 11, respectively) who were administered a single 10-g exenatide injection or placebo in a single-blinded, crossover design showed increased satiety, lowered glucose level, and insulinotropic effects [8]
They are not inevitable or irreversible, but they do warrant attention rather than being treated as an acceptable side effect to push through
2022;375:eabm9609
Large-scale human clinical trials on GHK-Cu remain limited
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