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Additionally, beta-blocker therapy including propranolol is considered a relative contraindication to subcutaneous allergen immunotherapy (SCIT), as it may both increase the risk of systemic reactions and reduce the effectiveness of adrenaline used to treat them

They actively interfere with medication absorption

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The high cost of these drugs prevents them from being widely used, especially in areas with lower incomes

Advantages: Incision hidden in the natural nose-lip crease (scar almost invisible once healed)