Regina Castaneda, found that women on both therapies achieved nearly 20% total body weight loss, while those on tirzepatide alone achieved closer to 15%
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Conversely, if your TSH rises, you may feel an increase in fatigue, brain fog, or cold intolerance
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They support metabolic health by: Improving insulin sensitivity Lowering A1C levels (a measure of long-term blood sugar) Reducing waist circumference Potentially improving cardiovascular risk factors Key Takeaway: Tirzepatide typically leads to greater weight loss in clinical settings due to its dual-hormone approach, but semaglutide remains a highly effective and widely used option for significant weight management