Genome-wide association studies of AD have similarly shown that the BDNF Val66Met is not a risk factor for AD [170]
The two tests scoring below 7.0 (6.1 and 6.4) were from May 2025, and both were affected by quantity overfill rather than purity issues at that level
However, in clinical trials involving natural compounds such as curcumin, resveratrol, and ginsenosides, these biomarkers have shown variable predictive value
Crozatier, M., Kongsuwan, K., Ferrer, P., Merriam, J., Lengyel J., and Vincent A., "Single amino acid exchanges in separate domains of the Drosophila serendipity delta zinc finger protein cause embryonic and sex biased lethality", Genetics 131: 905-916 (1992)
Honigberg MC, Chang LS, McGuire DK, Plutzky J, Aroda VR, Vaduganathan M