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Gallic acid primarily occurs as esters such as alkyl esters (methyl, propyl, and octyl gallate) and the catechin derivatives such as epicatechin gallate, epicatechin, and gallocatechin gallate [207]
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Therefore, higher doses of oral vitamin B12 can still be used in these patients to ensure normal levels of B12
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Despite the differences in the findings of these studies ( Table 2 ), the results do suggest that long-term (6 months) and adequate-dose vitamin D supplementation may reduce SF in patients with DRE, but this requires confirmation in larger, prospective trials
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