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Some continue indefinitely with maintenance protocols, others cycle on and off based on seasonal needs or life circumstances, and still others transition to preventive protocols with less frequent dosing after achieving desired benefits

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Mechanistically, ALC exerts its antidepressant effects via multiple pathways, including enhancement of mitochondrial function, upregulation of brain-derived neurotrophic factor (BDNF), modulation of glutamatergic neurotransmission, and epigenetic regulation of gene expression involved in mood regulation

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