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Adults with Overweight & Comorbidities: Individuals with a BMI of 27 kg/m or higher who also have at least one weight-related medical condition, such as hypertension (high blood pressure), type 2 diabetes, or dyslipidemia (high cholesterol)
Clinical data from the SURMOUNT-1 trial showed that gastrointestinal adverse events were dose-dependent: 39% at 5 mg, 46% at 10 mg, and 49% at 15 mg
Surgeons generally look for weight fluctuations of less than 5 pounds over a 3-month period as evidence of true stability
Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes
The primary risk is therapeutic failurepatients may experience rising blood glucose levels, inadequate appetite suppression, or weight regain if using compromised medication
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