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Sex-stratified subgroup analyses of epigenetic aging outcomes were not pre-specified and the study was not powered to detect sex-specific effects
Willow , for example, ran ads encouraging patients to cancel their gym membership and promised rapid weight lossmessaging that directly contradicts clinical guidelines and feeds into unhealthy narratives (they also prescribe to patients regardless of BMI)
After two years (120 weeks), the patients retained roughly one-third of their original weight loss (5.6% of the original 17.3% loss)
Real-world results vary based on dose, lifestyle, baseline weight, and adherence
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