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[11] [12] Patients with pre-existing gallstones discovered incidentally before starting GLP-1 therapy should discuss the risks and benefits with their healthcare provider, as the presence of asymptomatic gallstones is not necessarily a contraindication to treatment

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319,320,321 These findings are in concordance with a substantial body of literature that consistently reports diminished SCFAs-producing species and SCFA levels in prodromal stage of PD and PD patients compared to healthy controls, which may be correlated with the clinical severity of PD

GLP-1s, also known as GLP-1 receptor agonists (GLP-1RAs), stimulate the release of insulin, keeping blood sugar levels normal [3,5,9]

These medications are intended to assist individuals struggling to lose weight through diet and exercise alone