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Alcohol may also raise the risk of rare but serious complications associated with tirzepatide, such as pancreatitis and kidney disease
The glucagon receptor activation leads to a direct increase in energy expenditure, something neither Tirzepatide nor Cagrilintide can do (at least not as effectively)
In the SUSTAIN 8 study, patients with T2DM exhibited a lean mass decrease of 2.3 kg alongside a total weight loss of 5.3 kg, resulting in 43.4% of weight loss attributable to lean mass, while the ratio of lean mass to total mass increased by 1.2% from the baseline [111]
SPIE 12680 , 1268021 (2023)
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