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Reduce if gastrointestinal symptoms remain severe after six or more weeks at a given dose level, if significant dehydration results from persistent vomiting or diarrhea, if heart rate increases beyond 15 beats per minute above baseline, or if the side effect burden is causing protocol abandonment
The choice depends on your health goals and how your body responds to the medication
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Cotadutide has been taken forward in clinical trial development (see below)
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