i haven't lost any weight on tirzepatide Loss Journey: Our Transformative Experience How Tirzepatide Helped A 24

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We later removed fog-1 from the background as we realised qz2 enhanced glp-1(gf) independently from fog-1

Contribution statement JIM contributed to the design of the study, constructed the model, performed the analysis and literature search, acquisition and interpretation of the data, and wrote and revised the manuscript

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However, in keeping with our data on receptor pharmacology, increasing the dose to 30 nmol kg 1 , tenfold higher than maximal doses from our studies, shows that tirzepatide does have insulinotropic activity in Glp1r -/- mice or in the presence of a GLP-1R antagonist 5 , demonstrating that tirzepatide can engage the GIPR in mouse beta cells at sufficiently high concentrations