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Somewhat unexpectedly, markers deduced from dementia only partially overlap with amino acid markers obtained from frailty patients with cognitive defects (16), so that frailty and dementia partly share the diminished cognitive markers

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Copper may become potential irritants when they are oxidized and causes the formation of free acids

Changes from Th2 to Th1 cytokine pattern have been demonstrated to counteract the airway hyperresponsiveness and bronchial inflammation (42)

The A-NPs@(SHK+Ce6) nanosystem incorporates CaCO3 nanoparticles to buffer excess H+ ions and alleviate suppressive conditions, while the loaded SHK peptide inhibits lactate production and synergizes with photodynamic therapy to repolarize TAMs toward the M1 phenotype ( Biomimetic approaches that leverage macrophage membranes for nanoparticle coating represent an emerging strategy to enhance targeting and immune modulation