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Tyrosinase the rate-limiting enzyme in melanin synthesis is inhibited by glutathione
Future Directions Important knowledge gaps remain
Metformin and acid-reducing drugs (e.g., omeprazole) can lower B12 absorption over time
USA 115 , E10797E10806 (2018)
9,10 Acetylcysteine, used in treating acetaminophen toxicity, is a substrate for glutathione synthesis and ultimately increases the amount of glutathione available to bind NAPQI and prevent damage to hepatocytes
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