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Either way, the practical implication is similar, and it is arguably the most consequential consideration for anyone planning future work: on the brain-access hypothesis, novel dual GLP-1/GIP agonists engineered specifically for brain entry would be more rational next candidates to test than repurposed diabetes drugs chosen for market availability
In addition, GLP-1 causes delayed gastric emptying, which leads to weight loss [43]
Lancet Glob Health 9(2):e161e169 Williams ME et al (2021) Cerebrospinal fluid immune markers and HIV-associated neurocognitive impairments: a systematic review
Some of the main known factors are related to androgens
Relationships between mitochondria and neuroinflammation: implications for alzheimers disease
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