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[8] The honest framing for both is that these are surrogate endpoints body weight, HbA1c, liver fat measured over trial-length horizons

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Notably, preclinical evidence suggests that FAK inhibitors can reverse HDAC inhibitor-induced NEDD9-dependent metastasis, implying the feasibility of a targeted combination strategy ( 4.5 Lung cancer In the treatment of lung cancer, HDAC inhibitors have also shown promising application prospects