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Metformin affects cortical bone mass and marrow adiposity in diet-induced obesity in male mice
Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA
Proc Natl Acad Sci U S A (2013) 110(40):16199204.10.1073/pnas.1306799110 110 HongEGKoHJChoYRKimHJMaZYuTYet alInterleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
There was also the problem that GLP-1 is degraded within minutes by the enzyme DPP-4
Frequency : Initially, treatments are usually scheduled 2-3 times a week, with a reduction to once a week for maintenance after 6-8 weeks
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