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instead, they state patients should discuss with their primary care physician and/or endocrinologist whether GLP-1 drug use should be ceased so that the risk of vision loss from NAION in their fellow eye is balanced with the hypoglycemic and cardiovascular benefits from treatment

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Subsequently, iron is released from transferrin and undergoes reduction to its divalent form by lysosomal reductases before being transported into the cytosol via divalent metal transporter 1 (DMT1) and transient receptor potential mucolipin (TRPML1/2), ultimately entering the cellular labile iron pool (LIP) [97]

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