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Gastrointestinal side effects include: Nausea (15-30% of patients depending on dose): Usually mild to moderate and decreasing over time Diarrhea (13-24%): May contribute to dehydration if persistent Vomiting (6-12%): More common at higher doses Constipation (5-17%): Can alternate with diarrhea in some patients Abdominal pain (6-10%): Typically mild and self-limiting Decreased appetite : An intended effect contributing to weight loss Hypoglycemia risk varies depending on concurrent medications
Itoh, Z
In high-fat-fed rats, [dA(2)]GLP-1/GcG reduced body weight nonfasting plasma glucose, and boosted circulating plasma insulin concentrations when given twice daily for 21 days
Local application of medicated powders and pastes for a period of 5-7 days gives good relief (see below for remedies)
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Price, J.W
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