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In studies, it acts on GHRH receptors in the anterior pituitary, stimulating endogenous release of growth hormone (GH) and increasing IGF-1 systemically and also locally in various tissues, with effects investigated in metabolism and body composition
Avoid electronics, sugar, caffeine, heavy foods, and stress close to the bed
Practical precautions for all patients include: Maintaining adequate hydration as part of overall health Staying physically active and avoiding prolonged immobility Continuing prescribed anticoagulation if already indicated for other conditions Discussing travel plans, as long flights or car trips may require movement strategies Reporting any new medications or supplements to healthcare providers For patients undergoing elective surgery while taking semaglutide, discussion with both the prescribing physician and surgeon is important regarding perioperative management
Mainly digestive
In the first 4-6 weeks, especially if you're new to structured exercise, err on the side of shorter sessions and lower intensity
