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Freeze-thaw: Avoid repeated freeze-thaw cycles of reconstituted solution
Topical GHK-Cu creams and serums have been studied extensively and they do work for surface-level skin improvement
Funding This study was supported by the Medical Science Research Program of Hebei Province (20220709), the Government Funded Clinical Medicine Excellent Talent Training Project (ZF2022034), and the Hebei Natural Science Foundation (H2022316005)
The combination model of the above three compounds (butin:caffeic acid: luteolin = 1:4:10) was established using a combination of pharmacological and statistical techniques to promote melanogenesis in B16F10 cells in vitro, and promote melanogenesis in zebrafish in vivo through the expression of melanin-related genes TYR, MITF, KIT and DCT [118]
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