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The potential relationship between GLP-1 receptor agonists like semaglutide and thyroid C-cell tumors has been observed in rodent studies, where dose-dependent and duration-dependent increases in thyroid C-cell tumors were noted
PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation
however, GHR ablation in broader neural populations did not produce additional effects as compared to AgRP GHR KO mice, emphasizing a crucial role of AgRP neurons mediating GH responses
Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, et al
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