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In addition, there is a likely analogy (see for review i.e., (Seiwerth et al., 2018)) with the attenuated fibrosis and scar formation in other tissues (i.e., the skin, muscle, tendon, and ligament) (Mikus et al., 2001

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The ubiquitin interacting motif-like domain of Met4 selectively binds K48 polyubiquitin chains