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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis
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The formulation is stable.
Translated by SuperSmart march 3 2024 I'm sorry, but it seems like the original text you provided is incomplete or missing
Iron and Alzheimer's disease: an update on emerging mechanisms
