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Yu ZY et al
Efficacy endpoints were change from baseline in HbA 1c and body weight (and, for the separate PIONEER 8 subgroup analysis, change from baseline in insulin dose) at the planned end of treatment (weeks 26, 52 or 78, according to the trial)
Methylcobalamin enhances red blood cell production, improves oxygen delivery, and supports healthy nerve function, helping to alleviate conditions like fatigue and neuropathy
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