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They target the underlying biology of hunger, with weight loss as the main goal rather than a side effect
In contrast to bariatric surgery, which addresses root causes and delivers lasting results, GLP-1 drugs provide only temporary solutions, potentially leading to medication reliance
Critically, GIP receptor activation in adipose (fat) tissue appears to enhance fat mobilization and energy expenditure beyond what GLP-1 can do alone which helps explain tirzepatides superior weight loss outcomes in clinical trials
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