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Timing matters tooinjecting in the evening or right after a meal sometimes reduces nausea compared to morning injections on an empty stomach
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These effects are thought to occur through GLP-1s influence on both peripheral (vagal) and central pathways, including the hindbrain, hypothalamus, and brain regions involved in motivation and reward, which help regulate appetite and metabolism [8, 14, 18]
Similar to the SGLT2 inhibitors [1, 4, 13], GLP-1RAs also mildly reduced systolic and diastolic blood pressure in the trials
Rodrgues et al
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