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10.1016/j.atherosclerosis.2014.12.016 Atherosclerosis 226 ThompsonP
Long-term results require a combination of smart supplementation and healthy daily habits
Recent studies have claimed clinical benefits in patients with heart and kidney failure, arthritis, and sleep apnea disorders, mediated in part through anti-inflammatory and metabolic pathways, with some benefits partly independent of the degree of weight loss achieved
Enzyme systems regenerate e.g., pyruvate dehydrogenase (PDH) is activated, lactate production decreases, glycolysis and TCA cycle proceed and energy supply is restored
rather, clinicians consider it alongside a broader assessment of mood, behavior, and functioning to determine whether it reflects an underlying condition like depression
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