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Recent phase 3 clinical trials show that people taking the highest doses lost an average of 28.7% of their body weight over 68 weeks, which is about 71 pounds
Some online weight loss providers use compounded or lower-quality medications with questionable effectiveness
Semaglutide is a GLP-1 receptor agonist that helps people lose weight by: Activating the brain's appetite centers to reduce hunger and food cravings
After the 30-pound loss, that deficit shrinks to just 100 calories, which is barely noticeable on the scale and easily wiped out by normal daily variation in water weight
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