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That said, musculoskeletal symptoms including joint discomfort, arthralgia, and back pain have been observed across the broader class of incretin-based therapies
However, the symptom duration is similar between the two medications (46 weeks at stable dose), and tirzepatides higher efficacy for weight loss (20.9% vs 14.9% mean reduction) offsets the modestly higher GI burden for most patients
[13] [14] This effect contributes to both the therapeutic benefits and gastrointestinal side effects of tirzepatide
Heres how to properly stop taking semaglutide
Stop the drug and call a prescriber for severe persistent abdominal pain, uncontrolled vomiting, or sudden vision changes
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