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Yes, generally speaking

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The original preclinical study used a GCGR antibody antagonist to isolate the GCGR contribution in DIO mice: GCGR blockade significantly blunted weight loss and blocked the LY3437943-induced increase in energy expenditure without affecting caloric-intake reduction

Additionally, nausea may lead to reduced fluid intake, potentially contributing to dehydration and decreased saliva production, though xerostomia is not listed as a recognised adverse reaction in the product information

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