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Hemmi, H

Without uridine, the cell compensates for pyrimidine shortage by over-activating ATP-consuming salvage pathways (UCK2, TK1, dCK), which potentially drives mitochondrial biogenesis to generate more ATP for these phosphorylation reactions 63

On the other hand, IGF-IR may trigger EMT via STAT3, FAK, and NF-kB [67, 68]

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Our Healthcare providers at Rivas Medical Weight Loss carefully consider these factors when prescribing GLP-1 agonists to ensure optimal efficacy and minimize potential side effects