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Rare but serious risks include pancreatitis and thyroid C-cell concerns in people with a family history of medullary thyroid carcinoma

Accordingly, any inference regarding clinical benefit or perioperative risk is speculative

Quick look at the key results According to clinical trial investigators, orforglipron: Led to significant weight reduction across all dosing groups Showed greater effects at the highest dose levels Helped lower blood sugar in people with diabetes Supported modest improvements in blood pressure Demonstrated mainly mild to moderate side effects The trial results suggest that the once-daily pill performs competitively with early GLP-1 injection studies

Work with a registered dietitian to ensure adequate nutrition through a balanced, individualized meal plan

If one approach doesn't work, try something else