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Medically reviewed by Chet Tharpe, MDBoard-certified physician Related Articles How Coenzyme Q10 (CoQ10) Interacts with Weight Loss Medications CoQ10 has no direct interaction with semaglutide or tirzepatide, but GLP-1s reduce fat intake and slow gastric emptying, which can lower CoQ10 absorption

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But, the schedule can change based on how well the patient is doing and ongoing checks