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1 Introduction There are many pine bark extracts on the market, from different pine tree species, from different countries and with different levels of efficacy for human health ( French maritime pine bark extract (Horphag Research) is the most researched pine bark extract with over 450 published studies and over 160 human clinical trials, including over 12.000 subjects ( The French maritime pine trees that are used for Pycnogenol grow in Les Landes de Gascogne, along the coast of southwest France ( Pycnogenol was found to contain mainly procyanidins, their monomers catechin and epicatechin, taxifolin as well as phenolic acids ( is standardized to 70 5% and thus meets the specifications for maritime pine extract, described in the United States Pharmacopeia (USP) ( , taxifolin, catechin, caffeic acid, ferulic acid and metabolite 1 [-(3,4-dihydroxy-phenyl)--valerolactone] have been detected in the blood plasma of volunteers ( Clinical research on Pycnogenol started over 40 years ago and various health benefits of Pycnogenol have been observed and investigated

Hair loss often occurs not only because of age or genetics but also because of poor hair health

This means the 10 to 200 mcg/kg doses that dominate the animal literature translate to a rough human equivalent of approximately 1.6 to 32 mcg/kg, or about 120 to 2,400 micrograms for a 75-kilogram adult

This study was able to corroborate the previously reported elevations of miR-122, but failed to replicate the earlier report for miR-192 (Starkey Lewis et al

When traveling, keep the vial in original packaging with the pharmacy label visible