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found that ferroptosis-induced ERS crosstalks ferroptosis with apoptosis by increasing the expression of the pro-apoptotic molecule PUMA (155)
Retatrutide activates three metabolic receptors: GLP-1 (appetite suppression and glucose control), GIP (fat metabolism and insulin regulation), and glucagon (energy expenditure and fat oxidation)
(Lausanne) 11 , 202 (2020)
These medications can help to improve liver health and reduce the risk of complications associated with NAFLD
For instance, semaglutide has been approved and is being researched for indications including obesity, T2DM, reducing cardiovascular risk, chronic kidney disease, NAFLD, and AD, indicating that the development of new indications could provide new growth opportunities for GLP-1 drugs
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