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Tirzepatide represents a next-generation approach to this problem

The review found that people with obesity tend to have less diverse gut bacteria than lean people

Digestive changes: Increased bowel movements or changes in stool consistency, again primarily from fiber and prebiotic ingredients

Here are some side effects you can expect based on some of their ingredients: Bitter orange (synephrine): May raise heart rate and blood pressure, increasing the risk of heart attack or stroke, especially in people with cardiovascular conditions or those using other stimulants

Tirzepatide, by contrast, showed no significant increase in biliary risk in the available data