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It is released by intestinal L-cells after a meal and, separately, by preproglucagon neurons in the nucleus tractus solitarius of the brainstem, which gives the peptide both a peripheral endocrine role and a central neural one

Kidney Int 80(3):282287 Funding The study medication was provided by Boehringer Ingelheim

Nature 579 , 279283 (2020)

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