In parallel, excessive QA-driven NMDAR activation impairs sarco/endoplasmic reticulum Ca-ATPase function, disrupting calcium homeostasis and intracellular signalling [148]
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However, further studies are needed to confirm their efficacy and clarify whether their therapeutic effects are truly mediated through antioxidant mechanisms
225 These medications can cause side effects such as headaches, low blood pressure, and nausea
found that glutamine and its dipeptides restored oxidative metabolism in neonatal hepatocytes impaired by septic mediators (H 2 O 2 , NO), likely through boosting glutathione synthesis rather than the Krebs cycle