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Because Accutane is regulated through the governments iPLEDGE program, all blood test results and birth control methods must be documented and updated monthly in the system before the prescription can be issued

Future studies should clarify how these agents should be managed before elective arthroplasty, whether perioperative interruption affects weight or glycemic stability, and whether coordinated medication management can reduce aspiration concerns without undermining preoperative optimization

However, no cases of hypoglycemia were reported in phase 2 trials

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