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Additionally, SCO was found to inhibit TLR4-mediated NF-B signaling pathway and the expression of TLR4, TNF-, IL-6 and IL-1 in LPS-stimulated alveolar macrophages, underscoring its efficacy in alleviating LPS-induced ALI (19)
doi: 10.1056/NEJMra0901217 120 HsuR.-J.YuW.-C.PengG.-R.YeC.-H.HuS
Note, endothelin per se, inhibited platelet aggregation and caused subarachnoid hemorrhage [27,28]
[PMID: 12514067] PubMed record related to this compound for laboratory literature review
Budd-Chiari syndrome is caused by clots which can also occlude other vessels like the coronary arteries
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