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Several problems can lead to a vitamin B12 or folate deficiency

Antioxidants are supportive, not standalone curesoptimize your baseline with nutrition, sleep, movement and minimal toxins first

Carnitine also plays a role in metabolic regulation, detoxification, and cell membrane stabilization.[ref] This article covers: Mitochondrial energy production from long-chain fatty acids How carnitine is synthesized, including genes involved Effect on weight, mental health, immune response, and bone health Genetic changes and inborn errors of metabolism Lifehacks and solutions for optimizing carnitine levels Carnitine in Mitochondrial Energy Production: The Carnitine Shuttle Carnitine plays a specific role in mitochondrial energy production

At the same time, since DNA synthetic-sensitive tests for anemia and erythrocyte size are routinely done in even simple medical test clinics (so that these folate mediated-biochemical effects are more often directly detected), the MTR dependent effects of B12 deficiency are becoming apparent not as anemia (as they were classically), but now mainly as an elevation of homocysteine in the blood and urine (homocysteinuria)

The weight tends to come back because: When weight returns, your blood pressure and cholesterol levels increase, too, which raises your risk for cardiovascular disease and other complications