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How to Prepare and Care for B12 Injection Treatments Before Your Appointment Stay hydrated before treatment Inform your provider about medications or supplements you are taking Eat a light meal if recommended After Your Appointment Resume normal activities shortly after treatment Avoid applying pressure to the injection site for several hours Follow your providers recommendations for ongoing B12 shots Some individuals may experience mild redness or tenderness at the injection site, which typically resolves quickly

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One thing that makes it unusual right off the bat: it's remarkably stable in stomach acid