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doi: 10.4172/2329-8847.1000166

INT-787 (Next-Gen FXR Agonist) is a compound with enhanced FXR selectivity and solubility compared to OCA and has entered clinical trials for SAH

Every dose and outcome figure comes from the Novo Nordisk trial programme (REDEFINE 1 and 2, the phase 2 dose-finding trial and the phase 1b combination study) or from their registry records

Several potential anti-fibrotic agents have shown promise in mitigating DIC

In an animal high-altitude model, phosphorylated DSIP improved spatial-memory and sleep-architecture markers, but sample size was not clearly reported and this was not a healthy-human trial [11]