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After 12 weeks, participants in the APCP group exhibited improved skin moisture and texture, and the NMF content of amino acids and total ceramides were significantly increased compared with placebo values

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Another possibly beneficial and important effect of DSIP is its importance in withdrawal from opioids, when, together with exogenously administered morphine, it was able to modulate opioid peptidergic systems, and in chronic pain, where the results of the study stated a significant reduction in pain attacks in patients with chronic pain and depressive states

Minimize exposure to moisture and repeated freezethaw cycles