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The PCOS-Insulin Connection Most Doctors Miss Your doctor probably told you that PCOS is about "cysts on your ovaries" or "hormone imbalance." What they likely didn't explain is that for up to 80% of women with PCOS, insulin resistance is driving the entire show

Of the factors that participate in the TSS pathway, cystathionine beta-synthase (CBS) and cystathionine -lyase (CSE) mediate the first two rate-limiting steps of TSS by condensing serine with homocysteine to cystathionine and then cysteine