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10.1164/rccm.201305-0908LE Am J Respir Crit Care Med
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Oxidative stress (OxS)/cellular damage Oxidative stress (OxS) is a nonspecific pathophysiological condition that reflects a redox imbalance between increased production of ROS (free radicals) and the inability of antioxidant defenses to neutralize the reactive intermediates or to repair the ensuing damage 179,180
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GHKs histidine residue provides nitrogen coordination sites that stabilize Cu in a square planar geometry, creating a complex with a dissociation constant (Kd) around 10 Mamong the highest copper-binding affinities of any naturally occurring peptide
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