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Jozi, F
and menstrual irregularities in women, as reproductive hormones are sensitive to energy availability
Ultimately, through the induction of cardiac fibroblast proliferation and the activation of matrix metalloproteinases, it triggers extracellular matrix remodeling, displaying profibrogenic properties
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A recent open label trial compared the efficacy of drugs currently used to lower ICP in IIH (amiloride, furosemide, spironolactone and topiramate) and found a marginal reduction in ICP with no difference between drugs [11]
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