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Human thyroxine-binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern

Cuando los investigadores administraron semaglutida a monos verdes vervet, unos primates que beben alcohol voluntariamente, los animales bebieron menos sin mostrar signos de nuseas ni cambios en la ingesta de agua

Because the drug remains in clinical development, long-term reproductive data are not yet available, and fertility outcomes were not a primary endpoint in the Phase 2 trials conducted to date

McCann et al., 2024)