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The primary outcome measure is time to first major cardiovascular event over five years of follow-up

Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis

Retatrutide efficacy The phase 3 randomised, doubleblind, placebocontrolled TRIUMPH-1 trial evaluated the safety and efficacy of retatrutide for the treatment of patients with obesity or overweight, moderate-to-severe obstructive sleep apnoea and obesity, and knee osteoarthritis pain

Both patterns are shown in the weekly grid above